Synthesis of ent-Seragakinone A

Significance

Seragakinone A was isolated from an unidentified marine fungus, which is in symbiosis with rhodophyta Ceratodictyon spongiosum, and was shown to exhibit both antifungal and antibacterial properties. The relative structure was determined using X-ray crystal structure analysis and extensive spectroscopic studies; however, the absolute stereochemical configuration was not determined.