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Synthesis 2011(20): 3235-3240  
DOI: 10.1055/s-0030-1260192
PAPER
© Georg Thieme Verlag Stuttgart ˙ New York

Synthesis of Benzimidazole-Fused Heterocycles by Intramolecular Oxidative C-N Bond Formation Using Hypervalent Iodine Reagents

Noriki Kutsumura*, Shinichi Kunimatsu, Kimiko Kagawa, Takashi Otani, Takao Saito*
Department of Chemistry, Faculty of Science, Tokyo University of Science, Kagurazaka, Shinjuku-ku, Tokyo 162-8601, Japan
Fax: +81(3)52614631; e-Mail: nkutsu@rs.kagu.tus.ac.jp; e-Mail: tsaito@rs.kagu.tus.ac.jp;
Further Information

Publication History

Received 20 June 2011
Publication Date:
24 August 2011 (online)

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Abstract

A straightforward approach by dehydrogenative C-N coupling between aryl C-H and N-H bonds using a hypervalent iodine reagent under mild conditions offers a versatile and convenient method for synthesizing various benzimidazole-fused heterocycles.

Key words

hypervalent iodine reagent - C-N bond forming cyclization - benzimidazole-fused heterocycles - straightforward synthesis - mild conditions

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