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Synthesis 2011(19): 3143-3151
DOI: 10.1055/s-0030-1260147
DOI: 10.1055/s-0030-1260147
PAPER
© Georg Thieme Verlag
Stuttgart ˙ New York
Synthesis of Quinoxaline Analogues
Further Information
Publication History
Received
31 May 2011
Publication Date:
01 August 2011 (online)


Abstract
Substituted tricyclic or tetracyclic quinoxalines, tricyclic pyridoquinoxalines and bis-quinoxalines were synthesized in high yields starting from cyclic ketones by the α-bromination of cyclic ketones with N-bromosuccinimide (NBS) followed by condensation of the resulting α-bromo ketones with 1,2-diaminobenzene, 3,4-diaminopyridine, or 3,3′-diaminobenzidine.
Key words
condensation - halogenation - tandem reactions - heterocycles - arenes
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