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Synthesis 2011(8): 1249-1254  
DOI: 10.1055/s-0030-1259968
PAPER
© Georg Thieme Verlag Stuttgart ˙ New York

A Palladium-Catalyzed Ullmann-Ziegler Cross-Coupling for Sterically Hindered Biaryls

Max P. Nüllen, Richard Göttlich*
Institut für Organische Chemie, Justus Liebig Universität Gießen, Heinrich Buff Ring 58, 35392 Gießen, Germany
Fax: +49(641)9934349; e-Mail: richard.goettlich@org.chemie.uni-giessen.de;
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Publikationsverlauf

Received 12 January 2011
Publikationsdatum:
24. März 2011 (online)

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Abstract

We present a facile and versatile biaryl cross-coupling procedure based on a modified Ullmann coupling that may be applied to a wide range of substrates. This even allows the coupling of sterically hindered substrates under mild reaction conditions.

Key words

biaryls - catalysis - copper - cross-coupling - palladium

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