Synthesis 2011(4): 669-673  
DOI: 10.1055/s-0030-1258416
PAPER
© Georg Thieme Verlag Stuttgart ˙ New York

Ring-Closing Metathesis Approach to 2H-2-Benzazepine-1,3-diones

Stéphane Lebruna,b, Axel Couture*a,c, Eric Deniaua,b, Pierre Grandclaudona,b
a Université Lille Nord de France, 59000 Lille, France
Fax: +33(3)20436309; e-Mail: axel.couture@univ-lille1.fr;
b USTL, Laboratoire de Chimie Organique Physique, EA CMF 4478, Bâtiment C3(2), 59655 Villeneuve d’Ascq Cedex, France
c CNRS, UMR 8181 ‘UCCS’, Bâtiment C3(2), 59655 Villeneuve d’Ascq Cedex, France
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Publication History

Received 1 December 2010
Publication Date:
19 January 2011 (online)

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Abstract

A series of diversely substituted 2H-2-benzazepine-1,3-diones were efficiently prepared from the unsaturated precursors, N-acyl-o-vinylbenzamides, through a ring-closing metathesis reaction. The parent compounds were easily obtained from the appropriate o-vinylbenzoic acids.

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