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DOI: 10.1055/s-0030-1258183
Achiral and α-Amino Acid Derived Dicationic Imidazoliophanes
Publication History
Publication Date:
16 July 2010 (online)
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Abstract
Achiral and chiral imidazoliophanes were prepared by N-alkylation of chiral imidazole derivatives featuring an α-amino acid motif and subsequent double quarternization of the imidazole N3-position of the corresponding precyclophanes. Eight new optically pure imidazoliophanes were synthesized in good yields, whereas the molecular structure of one achiral analogue was confirmed by X-ray analysis.
Key words
cyclophanes - imidazoliophanes - amino acids - chiral pool - ligands
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- Supporting Information
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References
CCDC 757647 contains the supplementary crystallographic data for this paper. These data can be obtained free of charge at www.ccdc.cam.ac.uk/conts/retrieving.html [or from the Cambridge Crystallographic Data Centre, 12 Union Road, Cambridge CB2 1EZ, UK; fax: +44(1223)336033, E-mail: deposit@ccdc.cam.ac.uk].