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DOI: 10.1055/s-0030-1253411
Stereotactically Treated Giant Perivascular Spaces in a 13-Year-Old Boy Mimicking Brain Tumor
Publication History
Publication Date:
18 June 2010 (online)
Introduction
Perivascular spaces (PVSs) of the brain, also known as Virchow-Robin spaces, are pia-lined cavities surrounding brain arteries and arterioles as they penetrate into the cerebral tissue [13] [16]. Cystic cavities have first been described in the literature in 1838, as small cavities in the globus pallidus and putamen [2].
In most patients, enlarged perivascular spaces do not cause neurological symptoms. In some patients, they can cause focal neurological symptoms and an extensive space-occupying effect which requires neurosurgical intervention [1] [6] [7] [17].
References
- 1 Davis GA, Fitt GJ, Kalnins RM. et al . Increased perivascular spaces mimicking frontal lobe tumor. J Neurosurg. 2002; 97 723
- 2 Dechambre A. Mémoire sur la curabilité du ramollissement cérebral. Gazette Médicale de Paris. 1838; 6 305-314
- 3 Derouesné C, Gray F, Escourolle R. et al . Expanding cerebral lacunae in a hypertensive patient with normal pressure hydrocephalus. Neuropathol Appl Neurobiol. 1987; 13 309-320
- 4 Elster AD, Richardson DN. Focal high signal on MR scans of the midbrain caused by enlarged perivascular spaces: MR-pathologic correlation. AJNR Am J Neuroradiol. 1991; 11 1119-1122
- 5 Homeyer P, Cornu P, Lucette L. et al . A special form of cerebral lacunae: expanding lacunae. J Neurol Neurosurg Psychiatry. 1996; 611 200-202
- 6 House P, Salzman KL, Osborn A. et al . Surgical considerations regarding giant dilations of the perivascular spaces. J Neurosurg. 2004; 100 820-824
- 7 Kanamalla US, Calabro F, Jinkins JR. Cavernous dilatation of mesencephalic Virchow-Robin spaces with obstructive hydrocephalus. Neuroradiology. 2000; 42 881-884
- 8 Laitinen LV, Chudy D, Tengvar M. et al . Dilated perivascular spaces in the putamen and pallidum in patients with Parkinson's disease scheduled for pallidotomy: a comparison between MRI findings and clinical symptoms and signs. Mov Disord. 2000; 15 1139-1144
- 9 Mascalchi M, Salvi F, Godano U. et al . Expanding lacunae causing triventricular hydrocephalus: report of two cases. J Neurosurg. 1999; 91 669-674
- 10 MacLullich AMJ, Wardlaw JM, Ferguson KJ. et al . Enlarged perivascular spaces are associated with cognitive function in healthy elderly man. J Neurol Neurosurg Psychiatry. 2004; 75 1519-1523
- 11 Ono Y, Suzuki M, Kayama T. et al . Multilobulated cystic formation in the brain stem with Benedikt's syndrome: case report. Neurosurgery. 1994; 34 726-729
- 12 Pappayannis CE, Saidon P, Rugilo CA. et al . Expanding Virchow Robin spaces in the midbrain causing hydrocephalus. AJNR Am J Neuroradiol. 2003; 24 1399-1403
- 13 Poirier J, Barbizet J, Gaston A. et al . Thalamic dementia. Expansive lacunae of the thalamo-paramedian mesencephalic area. Hydrocephalus caused by stenosis of the aqueduct of Sylvius. Rev Neurol (Paris). 1983; 139 349-358
- 14 Rohfls J, Riegel T, Khalil M. et al . Enlarged perivascular spaces mimicking multicystic brain tumors. J Neurosurg. 2005; 02 1142-1146
- 15 Saeki N, Stao M, Kubota M. et al . MR imaging of normal perivascular space expansion at midbrain. Am J Neuroradiol. 2005; 26 566-571
- 16 Salzman KL, Osborn AG, House P. et al . Giant tumefactive perivascular spaces. AJNR Am J Neuroradiol. 2005; 26 298-305
- 17 Schroeder HWS, Gaab MR, Warzok RW. Endoscopic treatment of an unusual multicystic lesion of the brain stem: case report. Br J Neurosurg. 1996; 10 193-196
- 18 Song CJ, Kim JH, Kier EL. et al . MR imaging and histologic features of subinsular bright spots on T2-weighted MR images: Virchow-Robin spaces of the extreme capsule and insular cortex. Radiology. 2000; 214 671-677
Correspondence
Dr. G. GrahovacMD
Clinical Hospital Dubrava
Neurosurgery Avenija Gojka Suska 6
10000 Zagreb
Croatia
Phone: +385/129/024 76
Fax: +385/129/024 76
Email: ggrahov@mef.hr