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Fortschr Neurol Psychiatr 2011; 79(2): 73-82
DOI: 10.1055/s-0029-1245622
Übersicht

© Georg Thieme Verlag KG Stuttgart · New York

Kognitive Leistungen und Adhärenzverhalten bei Patienten mit schizophrenen Psychosen

Adherence and Cognitive Performance in SchizophreniaA. Spiekermann1 , M. Schulz1 , J. Behrens2 , M. Driessen1 , E. Rahn3 , T. Beblo1
  • 1Abteilung für Forschung, Qualitätssicherung und Dokumentation, Klinik für Psychiatrie und Psychotherapie Bethel
  • 2Institut für Gesundheits- und Pflegewissenschaft, Martin-Luther-Universität Halle-Wittenberg
  • 3Abteilung Allgemeinpsychiatrie, LWL-Kliniken Warstein und Lippstadt
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Publication History

Publication Date:
24 November 2010 (online)

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Zusammenfassung

Hintergrund: Es ist bekannt, dass viele Patienten mit schizophrenen Erkrankungen Non-Adhärenz bzgl. der regelmäßigen Einnahme antipsychotischer Medikamente zeigen. Zum anderen weisen viele Studien auf kognitive Defizite der Betroffenen hin. In dieser Übersichtsarbeit sollen die Ergebnisse von Studien, die den Zusammenhang von Non-Adhärenz und kognitiver Leistungsfähigkeit untersucht haben, gegenübergestellt werden. Methode: Mittels einer systematischen Literaturrecherche wurde der Zusammenhang kognitiver Leistungsparameter mit dem Ausmaß der Adhärenz schizophrener Patienten untersucht. Ergebnisse: Es konnten 18 Studien ermittelt werden, in welchen der Zusammenhang zwischen kognitiver Leistungsfähigkeit und adhärentem Verhalten untersucht wurde. Ein Großteil der Studien belegt, dass Patienten mit stärkeren kognitiven Beeinträchtigungen weniger adhärentes Verhalten zeigen. Die möglichen kausalen Mechanismen dieses Zusammenhangs werden diskutiert.

Abstract

Background: It is known that many patients with schizophrenia show non-adherence with regard to antipsychotic medication. Furthermore, many studies indicate cognitive deficits in schizophrenic patients. In this review, we compare the results of studies examining the relationship of non-adherence and cognitive performance. Method: Based on a systematic literature review, the impact of cognitive performance on the adherence behaviour of patients with schizophrenia was examined. Results: We found 18 studies analysing the impact of cognitive performance on adherence behaviour. Most studies indicated that patients with stronger cognitive impairments show lower adherence behaviour. Possible causal mechanisms are discussed.

Schlüsselwörter

Adhärenz - Compliance - Schizophrenie - Neurokognition - kognitive Beeinträchtigungen

Keywords

adherence - compliance - schizophrenia - neurocognition - cognitive impairment

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Alexa Spiekermann

Abteilung für Forschung, Qualitätssicherung und DokumentationKlinik für Psychiatrie und Psychotherapie Bethel

Remterweg 69 / 71

33617 Bielefeld

Email: alexa_spiekermann@gmx.de