Planta Med 2009; 75 - PH43
DOI: 10.1055/s-0029-1234760

In-vitro anticandidal activity of endemic Salvia potentillifolia Boiss & Heldr. Ex Bentham and Origanum hypericifolium O. Schwartz & P.H. Davis in Turkey

T Kartal 1, A Celik 1, C Engin 2, I Arslan 1
  • 1Pamukkale University, Faculty of Arts and Science, Department of Biology Denizli, Turkey
  • 2Pamukkale University, Faculty of Medicine, Department of Microbiology, Denizli, Turkey

The present study established baseline data on anticandidal lytic activities of endemic species Origanum hypericifolium and Salvia potentillifolia naturally distributed Denizli and its environment. Steam distillation was used to isolate the unfatty polar part and clinical isolated Candida spp. strains were subcultured to sabouraud dextrose agar. Lytic anti-candidal activities of unfatty polar parts were evaluated by enzym linked calorimetric method [1] against 93 clinical isolates belong to Candida albicans, C. tropicalis, C. glabrata, C. krusei, C. kefyr and C. parapsilosis. As a result, two (2.15%) strains of Candida glabrata amongst tested patogenic 93 clinical isolates of Candida strains were found to be sensitive to S. potentillifoli. However, each strain of Candida albicans and Candida tropicalis was found to be sensitive to Origanum hypericifolium. Results indicated that O. hypericifolium and S. potentillifolia had a potential of being used in food and medicine because of its anticandial activity.

References: [1]Sally, N. et al. (2002) J. Micro. Methods 49:1–9.