Medicinal preparations on the basis of vegetable phenolic compounds

Azotemic preparation Flaronin was produced on the basis of individual flavonoid glycoside – robinin which is kaempferol 3-O-β-robinobiosyl-7-O-α-L-rhamnopyranoside isolated from Astragalus falcatus. Flaronin stimulates the nitrogen releasing function of kidneys, reduces the amount of residual nitrogen, urea and creatinine in blood, and promotes diuresis. Flaronin is successfully used for treatment of nephratonia complicated with pyelonephritis and other nephritic diseases [1]. The leaves of Pueraria hirsute are proposed as another vegetable raw material for production of Flaronin [2].

The phenolic compounds of the Caucasian endemic Rhododendron ungernii, consisting of flavonoids, catechins and leucoanthocyanins, completely inhibited the herpes virus in experiment. From the pure sum of phenolic compounds, preparation Rhodopes was produced in the form of ointment. The clinical examinations showed high therapeutic efficiency of Rhodopes. The preparation is recommended for treatment of all types of herpes simplex and chickenpox, herpes zoster, genital herpes, primary and recurrent herpetic stomatitis etc. [3].

From Satureja hortensis hypoglycemic preparation Saturin was produced. It consists of flavonoids and phenylpropanoids, mainly of luteolin glycosides and rosmarinic acid. Saturin reliably decreases the blood sugar. It is used as a food supplement in mild and medium cases of non-insulin-dependent diabetes independently or in combination with appropriate antidiabetes medication [4].

References: [1] Alania, M. et al. (2002) Flavonoids of some species Astragalus L. from Georgia. Tbilisi, Mecniereba.

[2] Kemertelidze, E. et al. (2008) Chem. Farm.J. 6(42):28–31.

[3] Kemertelidze, E. et al. (2007) Chem. Farm.J. 1(41):10–13.

[4] Kemertelidze, E. et al. (2004) Chem. Farm.J. 6(38):33–35.