Semin Neurol 2009; 29(3): 247-255
DOI: 10.1055/s-0029-1223878
© Thieme Medical Publishers

Neuropsychiatric Sequelae of Traumatic Brain Injury

Jeffrey Nicholl1 , W. Curt LaFrance2
  • 1Department of Psychiatry and Neurology, Tulane University School of Medicine, New Orleans, Louisiana
  • 2Division of Neuropsychiatry and Behavioral Neurology, Brown Medical School/Rhode Island Hospital, Providence, Rhode Island
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Publication History

Publication Date:
23 June 2009 (online)

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ABSTRACT

The prevalence of traumatic brain injury (TBI) is increasing, particularly in the population of veterans. Many times, the motor and sensory consequences of TBI are addressed, but the post-TBI neuropsychiatric sequelae, which may be as, or even more devastating than the motor and sensory deficits, are left unattended. Cognitive, mood, anxiety, thought, impulse, and substance disorders, and a variety of personality disorders can be seen following TBI. The neuropsychiatric sequelae of TBI not only interfere with day-to-day function, but can severely impede rehabilitation efforts. To date, there have been few large-scale studies looking at the effectiveness of the various treatment modalities, including psychotherapeutic and pharmacological interventions.