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Synfacts 2010(3): 0270-0270
DOI: 10.1055/s-0029-1219249
DOI: 10.1055/s-0029-1219249
Synthesis of Natural Products and Potential Drugs
© Georg Thieme Verlag
Stuttgart ˙ New York
Synthesis of Zoanthenol
Y. Takahashi, F. Yoshimura, K. Tanino*, M. Miyashita*
Hokkaido University, Sapporo, Japan
Further Information
Publication History
Publication Date:
18 February 2010 (online)
![](https://www.thieme-connect.de/media/synfacts/201003/lookinside/thumbnails/10.1055-s-0029-1219249-1.jpg)
Significance
The zoanthamine alkaloids, a family of marine metabolites, have a novel array of structures and show potential anti-osteoporotic properties. The synthesis of norzoanthamine and zoanthamine has been previously published by the same group and now a route to zoanthenol has been completed by using a tautomerization strategy from the manipulation of a previously prepared precursor for the other natural products.