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Synfacts 2010(2): 0216-0216
DOI: 10.1055/s-0029-1219069
DOI: 10.1055/s-0029-1219069
Metal-Mediated Synthesis
© Georg Thieme Verlag
Stuttgart ˙ New York
Copper-Catalyzed Arene C-H Activation and Cross-Coupling
H.-Q. Do, O. Daugulis*
University of Houston, USA
Further Information
Publication History
Publication Date:
21 January 2010 (online)
Significance
An efficient, highly regioselective one-pot protocol for the activation and cross-coupling of aromatic C-H bonds was developed. Various electron-rich heteroarenes and arenes could thus be coupled with electron-poor arenes possessing more than one electron-withdrawing group.