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Synfacts 2010(2): 0245-0245  
DOI: 10.1055/s-0029-1219055
Polymer-Supported Synthesis
© Georg Thieme Verlag Stuttgart ˙ New York

Direct Reductive Amination with Gum Acacia Stabilized Pd Nanoparticles

Contributor(s): Yasuhiro Uozumi, Tsubasa Muto
B. Sreedhar*, P. S. Reddy, D. K. Devi
Indian Institute of Chemical Technology, Hyderabad, India
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Publication History

Publication Date:
21 January 2010 (online)

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Significance

Gum acacia stabilized palladium nanoparticles (GA-Pd nanoparticles) were prepared and applied to a reductive amination reaction. The GA-Pd nanoparticles catalyzed the direct one-pot reductive amination of aldehydes 2 with nitroarenes 1 under atmospheric pressure of hydrogen to give the corresponding amines 3 in up to 96% yield (eq. 2, 18 examples).