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Synthesis 2010(10): 1697-1701
DOI: 10.1055/s-0029-1218738
DOI: 10.1055/s-0029-1218738
PAPER
© Georg Thieme Verlag
Stuttgart ˙ New York
Synthesis of Bis(tetronic acid)s via Double Dieckmann Condensation
Further Information
Received
12 February 2010
Publication Date:
15 April 2010 (online)
Publication History
Publication Date:
15 April 2010 (online)
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Abstract
A practical, straightforward synthesis of several bis(tetronic acid)s from a common precursor, dimethyl l-tartrate, is described. It involves a double Dieckmann condensation using tetrabutylammonium fluoride. The radical scavenging capacities of these compounds are measured.
Key words
condensation - cyclization - esters
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