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Synlett 2010(1): 107-110
DOI: 10.1055/s-0029-1218537
DOI: 10.1055/s-0029-1218537
LETTER
© Georg Thieme Verlag
Stuttgart ˙ New York
A Synthesis of the C3-C15 Fragment of the Archazolids
Weitere Informationen
Received
8 July 2009
Publikationsdatum:
02. Dezember 2009 (online)
Publikationsverlauf
Publikationsdatum:
02. Dezember 2009 (online)
Abstract
Ring-closing metathesis and an allylation-elimination reaction sequence have been used to complete a synthesis of the conjugated triene subunit of the archazolids.
Key words
stereoselective synthesis - tandem reactions - allylations - eliminations - metathesis
- Supporting Information for this article is available online:
- Supporting Information
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References and Notes
The stereochemistry was later confirmed by NMR analysis. See Supporting Information for details.
16A similar conjugated triene product was obtained with comparable yield and selectivity from an acyclic substrate (Scheme 6); see Supporting Information for details.