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Synfacts 2009(10): 1098-1098  
DOI: 10.1055/s-0029-1217932
Synthesis of Materials and Unnatural Products
© Georg Thieme Verlag Stuttgart ˙ New York

Electrocyclization Route to Isoindoline Nitroxides

Contributor(s): Timothy M. Swager, David M. Chenoweth
T. Kálai, J. Jekõ, K. Hideg*
University of Pécs, ICN Hungary, Tiszavasvári and College of Nyíregyháza, Hungary
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Publication History

Publication Date:
22 September 2009 (online)

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Significance

Stable nitroxide-free radicals find widespread use as spin traps and labels in chemistry and biology. In this report a new route to isoindoline nitroxides was developed utilizing an electrocyclization-oxidation strategy to forge the isoindoline ring system.