Download PDF
Synfacts 2009(10): 1149-1149  
DOI: 10.1055/s-0029-1217886
Metal-Mediated Synthesis
© Georg Thieme Verlag Stuttgart ˙ New York

Naphthalenes via Gold(III)-Catalyzed Addition of Aryl Alkynes to Ketones

Contributor(s): Paul Knochel, Andrei Gavryushin
R. Balamurugan*, V. Gudla
University of Hyderabad, India
Further Information

Publication History

Publication Date:
22 September 2009 (online)

    Permissions and Reprints

Significance

Regioselective formation of polysubstituted naphthalenes is an important and challenging synthetic task. Reaction of benzylic carbonyl compounds with aryl alkynes under soft Lewis acid catalysis affords a variety of polysubstituted naphthalenes in good yields. This reaction can be quite useful for the preparation of fused polyarenes.