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Synfacts 2009(10): 1178-1178  
DOI: 10.1055/s-0029-1217877
Polymer-Supported Synthesis
© Georg Thieme Verlag Stuttgart ˙ New York

Synthesis of Propargylamines with Copper Ferrite Nanoparticles

Contributor(s): Yasuhiro Uozumi, Tsubasa Muto
M. L. Kantam*, J. Yadav, S. Laha, S. Jha
Indian Institute of Chemical Technology, Hyderabad and Jadavpur University, Kolkata, India
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Publication History

Publication Date:
22 September 2009 (online)

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Significance

Copper ferrite (CuFe2O4) nanoparticles catalyzed the three-component coupling of aldehydes 1, amines 2, and alkynes 3 to give the corresponding propargylamines 4 in up to 91% yield (17 examples). The catalyst was magnetically recovered and reused twice without significant loss of the catalytic activity.