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Synlett 2009(11): 1791-1794
DOI: 10.1055/s-0029-1217362
DOI: 10.1055/s-0029-1217362
LETTER
© Georg Thieme Verlag
Stuttgart ˙ New York
Synthesis of Propargylamines by Three-Component Coupling of Aldehydes, Amines and Alkynes Catalyzed by Magnetically Separable Copper Ferrite Nanoparticles
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Publikationsverlauf
Publikationsdatum:
12. Juni 2009 (online)


Abstract
An efficient three-component coupling of aldehydes, amines and alkynes has been developed to prepare propargylamines in nearly quantitative yields using magnetically separable copper ferrite nanoparticles as catalyst. Structurally divergent aldehydes and amines were converted into the corresponding propargylamines. The reaction does not require any co-catalyst.
Key words
copper ferrite nanoparticles - propargylamines - three-component coupling - reusability