Synlett 2009(9): 1387-1390  
DOI: 10.1055/s-0029-1217162
LETTER
© Georg Thieme Verlag Stuttgart ˙ New York

Disubstituted Benzenes from Acyclic Precursors by a [5+1] Annulation

David S. B. Daniels, John M. Brown, Maud Gayral, Yingjian Xu, Malcolm I. Stewart*
Chemistry Research Laboratory, Mansfield Road, Oxford OX1 3TA, UK
Fax: +44(1865)285002; e-Mail: malcolm.stewart@chem.ox.ac.uk;
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Publikationsverlauf

Received 22 January 2009
Publikationsdatum:
13. Mai 2009 (online)

Abstract

Horner-Wadsworth-Emmons reaction of stannylvinylphosphonates with aldehydes and mild thermal cyclisation provides disubstituted arylstannanes. Subsequent Stille coupling leads to regiospecific synthesis of m- and p-terphenyls.