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Synthesis 2009(22): 3869-3879
DOI: 10.1055/s-0029-1216995
DOI: 10.1055/s-0029-1216995
PAPER
© Georg Thieme Verlag
Stuttgart ˙ New York
Reactions of 3-(Polyfluoroacyl)chromenones with Heterocyclic Amines: Novel Synthesis of Polyfluoroalkyl-Containing Fused Pyridines
Weitere Informationen
Received
19 May 2009
Publikationsdatum:
08. September 2009 (online)
Publikationsverlauf
Publikationsdatum:
08. September 2009 (online)
![](https://www.thieme-connect.de/media/synthesis/200922/lookinside/thumbnails/10.1055-s-0029-1216995-1.jpg)
Abstract
The selectivity of the reactions of 3-(polyfluoroacyl)-4H-chromen-4-ones with a wide range of aminoheterocycles and arylamines has been evaluated. The method described facilitates access to polyfluoroalkyl-containing fused pyridines.
Key words
aminoheterocycles - arylamines - condensation - chroman-4-ones - polyfluoroalkyl - fused pyridines
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References
Crystallographic data (excluding structure factors) for the structures reported in this paper have been deposited with the Cambridge Crystallographic Data Centre as supplementary publication no. CCDC 721116 for 3n, CCDC 721117 for 4a, and CCDC 721118 for 5g can be obtained free of charge on application to CCDC, 12 Union Road, Cambridge CB2 1EZ, UK [fax: +44 (1223)336033; e-mail: deposit@ccdc.cam.ac.uk].