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Synthesis 2009(13): 2278-2282
DOI: 10.1055/s-0029-1216865
DOI: 10.1055/s-0029-1216865
PAPER
© Georg Thieme Verlag
Stuttgart ˙ New York
Iron(III) Chloride in Ethanol-Water: Highly Efficient Catalytic System for the Synthesis of Garcia Gonzalez Polyhydroxyalkyl- and C-Glycosylfurans
Further Information
Received
13 November 2008
Publication Date:
08 June 2009 (online)
Publication History
Publication Date:
08 June 2009 (online)
![](https://www.thieme-connect.de/media/synthesis/200913/lookinside/thumbnails/10.1055-s-0029-1216865-1.jpg)
Abstract
An efficient method has been developed for the synthesis of Garcia Gonzalez polyhydroxyalkyl- and C-glycosylfurans in excellent yields from unprotected sugar aldoses with β-keto esters by Knoevenagel condensation in the presence of anhydrous iron(III) chloride.
Key words
d-glucose - β-keto esters - Knoevenagel reaction - furans - carbohydrates
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