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Synthesis 2009(13): 2179-2183
DOI: 10.1055/s-0029-1216857
DOI: 10.1055/s-0029-1216857
PAPER
© Georg Thieme Verlag
Stuttgart ˙ New York
A Simple Method for the Synthesis of 3-Arylthieno[2,3-b]pyridines via Iodine-Mediated Cyclization of 3-(1-Arylalkenyl)-2-[(1-phenylethyl)sulfanyl]pyridines
Weitere Informationen
Received
20 January 2009
Publikationsdatum:
02. Juni 2009 (online)
Publikationsverlauf
Publikationsdatum:
02. Juni 2009 (online)
![](https://www.thieme-connect.de/media/synthesis/200913/lookinside/thumbnails/10.1055-s-0029-1216857-1.jpg)
Abstract
3-Arylthieno[2,3-b]pyridines are synthesized in a short four-step sequence from readily available 2-bromopyridines. The final and key step of the reported method involves an iodine-mediated 5-endo cyclization of 3-(1-arylalkenyl)-2-[(1-phenylethyl)sulfanyl]pyridines.
Key words
thieno[2,3-b]pyridines - iodine - 2-bromopyridines - cyclization - heterocycles
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