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DOI: 10.1055/s-0029-1216811
On the Resolution of Secondary Phosphine Oxides via Diastereomeric Complex Formation: The Case of tert-Butylphenylphosphine Oxide
Publikationsverlauf
Publikationsdatum:
25. Mai 2009 (online)
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Abstract
The secondary phosphine oxide, t-BuPhHP=O, the most prominent chiral member of this compound class, has been resolved in high yield and with excellent ee. This resolution discloses an efficient route to enantiopure phosphorus compounds.
Key words
secondary phosphine oxide - phosphinous acid - asymmetric catalysis - resolution - chiral ligand - P-chiral compounds
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References
Present address: School of Chemistry, University of Leeds, Leeds, LS2 9JT, UK.
33CCDC-719981 (A) and CCDC-719982 (B) contain the supplementary crystallographic data for this paper. These data can be obtained free of charge at www.ccdc.cam.ac.uk/conts/retrieving.html [or from the Cambridge Crystallographic Data Centre, 12 Union Road, Cambridge CB2 1EZ, UK; fax: +44(1223)336 033; E-mail: deposit@ccdc.cam.ac.uk.