Subscribe to RSS
Please copy the URL and add it into your RSS Feed Reader.
https://www.thieme-connect.de/rss/thieme/en/10.1055-s-00000131.xml
Synfacts 2009(6): 0677-0677
DOI: 10.1055/s-0029-1216767
DOI: 10.1055/s-0029-1216767
Organo- and Biocatalysis
© Georg Thieme Verlag
Stuttgart ˙ New York
The 1,2,4-Triazole Anion as an Acyl Transfer Catalyst
X. Yang, V. B. Birman
Washington University, St. Louis, USA
Further Information
Publication History
Publication Date:
25 May 2009 (online)
![](https://www.thieme-connect.de/media/synfacts/200906/lookinside/thumbnails/10.1055-s-0029-1216767-1.jpg)
Significance
Yang and Birman report that the 1,2,4-triazole anion is an acyl transfer catalyst. The acetylation proved to be effective for amines, alcohols and oxazolidinones. This catalyst is also suitable for transesterification as well as for aminolysis, where unactivated esters can be transformed into the corresponding products. Mechanistic alternatives have been investigated.