Endoscopy 2009; 41(4): 374-376
DOI: 10.1055/s-0029-1214488
Case report

© Georg Thieme Verlag KG Stuttgart · New York

Long-term outcome after endoscopic resection in patients with hypopharyngeal carcinoma invading the subepithelium: a case series

Y.  Shimizu1 , T.  Yoshida1 , M.  Kato2 , S.  Ono2 , M.  Nakagawa2 , A.  Homma3 , N.  Oridate3 , M.  Asaka1
  • 1Third Department of Internal Medicine, Hokkaido University Hospital, Sapporo, Japan
  • 2Division of Endoscopy, Hokkaido University Hospital, Sapporo, Japan
  • 3Department of Otolaryngology, Hokkaido University Hospital, Sapporo, Japan
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Publikationsverlauf

submitted21 November 2008

accepted after revision2 January 2009

Publikationsdatum:
01. April 2009 (online)

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Patients with early stage hypopharyngeal carcinoma can be treated with endoscopic resection. However, strict indication for endoscopic resection in cases of hypopharyngeal carcinoma is unclear. In this paper, we evaluated the long-term outcome after endoscopic resection in patients with hypopharyngeal carcinoma invading the subepithelium. Among 16 patients with hypopharyngeal carcinoma who underwent endoscopic resection, eight patients who were histologically confirmed to have tumors with shallow invasion of the subepithelium were studied. Depth of tumor invasion in the subepithelium in those patients ranged from 300 to 720 µm (mean ± SD, 490 ± 140 µm). During a median follow-up period of 40 months, none of the eight patients had local recurrence or metastasis. Kaplan-Meier estimates of relapse-free survival rates at 5 years in the eight patients were 100 %. The results of this study suggest that hypopharyngeal carcinoma with slight invasion to the subepithelium can be successfully treated by endoscopic resection.