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Exp Clin Endocrinol Diabetes 1992; 99(2): 108-109
DOI: 10.1055/s-0029-1211147
DOI: 10.1055/s-0029-1211147
Original
© J. A. Barth Verlag in Georg Thieme Verlag KG Stuttgart · New York
Evidence for Pulsatile Secretion of Human Atrial Natriuretic Peptide in Healthy Subjects
Further Information
Publication History
1991
Publication Date:
15 July 2009 (online)
Summary
The secretion pattern of human atrial natriuretic peptide (hANP) was investigated in 8 healthy male volunteers. Blood was drawn in 2 minute intervals for 90 minutes and in a second study in 4 minute intervals for 180 minutes. Base-line hANP plasma levels varied in a pulsatile secretion pattern of regular pulses every 9 ± 1 minutes. Additionally long-term oscillations of 34 ± 4 minutes were found.
These data suggest that under basal conditions hANP varies in a pulsatile fashion.
Key words
Human atrial natriuretic peptide (hANP) - Pulsatile secretion pattern