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Exp Clin Endocrinol Diabetes 1990; 95(2): 192-196
DOI: 10.1055/s-0029-1210951
Original

© J. A. Barth Verlag in Georg Thieme Verlag KG Stuttgart · New York

The Response of Rat Adrenal Zona Fasciculata and Zona Reticularis to Oxytocin Treatment

Bosiljka Plećaš, Mirjana Hristić1 , Danica Jovović, Andielija Popović
  • Department of Physiology, Faculty of Pharmacy, Belgrade/Yugoslavia
  • 1Institute for Biological Research, Belgrade/Yugoslavia
Further Information

Publication History

1989

Publication Date:
16 July 2009 (online)

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Summary

The response of the adrenal zona fasciculata (ZF) and zona reticularis (ZR) to oxytocin (OT) was examined in male rats using a stereological method. The 10-day administration of 0.25 IU OT/100 g daily caused an enlargement of ZF due to cell hypertrophy associated with striking lipid accumulation. The volume of ZR was decreased, this change being the consequence of the reduced cell population. The possible site of OT action is discussed.

Key words

Oxytocin - Adrenal cortex - Stereology