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Exp Clin Endocrinol Diabetes 1988; 92(6): 357-362
DOI: 10.1055/s-0029-1210826
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© J. A. Barth Verlag in Georg Thieme Verlag KG Stuttgart · New York

Relationship between Parathyroid Hormone and Pituitary-Testicular Axis in Patients on Maintenance Hemodialysis

M. Bogićević, V. Stefanović
  • Institute of Nephrology and Hemodialysis, Faculty of Medicine, Niš/Yugoslavia
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Publication History

1988

Publication Date:
16 July 2009 (online)

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Summary

The effect of secondary hyperparathyroidism upon hormones of the pituitary testicular axis was studied in 39 end-stage kidney disease male patients on maintenance hemodialysis. In hemodialysed patients the mean serum levels of PTH, prolactin and LH were significantly increased, that of testosterone decreased, and of FSH unchanged. PTH and prolactin values were found to be dependent upon residual renal function measured by 24 h urine output. A significant positive correlation was found between the serum levels of PTH and LH (r = 0.405) and between PTH and serum levels of prolactin (r = 0.401). Secondary hyperparathyroidism is suggested to be responsible, at least partly, for sexual dysfunction in male patients on maintenance hemodialysis.

Key words

Parathyroid hormone - Pituitary-testicular axis - Hemodialysis