Download PDF
Exp Clin Endocrinol Diabetes 1987; 89(3): 368-374
DOI: 10.1055/s-0029-1210664
Original

© J. A. Barth Verlag in Georg Thieme Verlag KG Stuttgart · New York

Islet Cell Antibodies and Viral Infections

K. Fedrlin, A. Otten, K. Helmke
  • III Medical Clinic and Policimic, Pediatvic Clinic, Justus Liebig University, Giessen/ FRG
Further Information

Publication History

1986

Publication Date:
16 July 2009 (online)

Also available at
  PDF Download  Permissions and Reprints

Summary

The sera of 127 non-diabetic children after mumps-infetion were investigated for the presence of islet cell antibodies and islet cell surface antibodies. The study also included 4 children who developed diabetes mellitus shortly after an active mumps vaccination. 21 of the non-diabetic children and four of the vaccinated children exhibited islet cell cytoplasmic antibodies. Islet cell surface antibodies were observed more frequently, namely in 43 out of 68 patients studied after mumps infection and in 32 out of 44 patients studied after different viral diseases. With one exception, none of the mumps-infected children and none of the other viral infected patients devloped diabetes mellitus.

Key words

Islet cell antibodies - Islet cell surface antibodies - Type I diabetes - Mumps viral infection - Mumps vaccination - Autoimmunity

      >