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Exp Clin Endocrinol Diabetes 1985; 86(6): 266-272
DOI: 10.1055/s-0029-1210496
DOI: 10.1055/s-0029-1210496
Original
© J. A. Barth Verlag in Georg Thieme Verlag KG Stuttgart · New York
Carbohydrate Metabolism in the Genital Organs of Adult Female Rhesus Monkeys: Effect of Prolonged Treatment with Centchroman, an Antiimplantation Agent
Further Information
Publication History
1984
Publication Date:
16 July 2009 (online)
![](https://www.thieme-connect.de/media/eced/198506/lookinside/thumbnails/10.1055-s-0029-1210496-1.jpg)
Summary
Weekly oral administration of centchroman at 1 and 2.5 mg/kg doses for 3, 6 or 12 months to adult female rhesus monkeys (Macaco, mulatto) significantly decreased glycogen content and activity of phosphorylase, glucokinase, lactate dehydrogenase and glucose 6-phosphate dehydro-genase enzymes in all the genital tract tissues. In general, the inhibition was dose and time dependent. No effect was, however, observed in the liver and serum.
Key Words
Centchroman - Macaque - Enzymes - Genital tract