Endoscopy 2009; 41(2): 175-178
DOI: 10.1055/s-0028-1119467
Case report

© Georg Thieme Verlag KG Stuttgart · New York

Impact of double-balloon endoscopy on the diagnosis of jejunoileal involvement in primary intestinal follicular lymphomas: a case series

N.  Higuchi1 , Y.  Sumida1 , K.  Nakamura1 , S.  Itaba1 , S.  Yoshinaga1 , T.  Mizutani1 , K.  Honda1 , K.  Taki1 , H.  Murao1 , H.  Ogino1 , K.  Kanayama1 , H.  Akiho1 , A.  Goto2 , Y.  Segawa2 , T.  Yao2 , R.  Takayanagi1
  • 1Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
  • 2Department of Anatomic Pathology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
Weitere Informationen

Publikationsverlauf

submitted 17 February 2008

accepted after revision 20 November 2008

Publikationsdatum:
12. Februar 2009 (online)

In recent years, primary gastrointestinal follicular lymphoma has been increasingly detected in the duodenum on esophagogastroduodenoscopy (EGD). Primary gastrointestinal follicular lymphomas are frequently distributed to multiple sites in the gastrointestinal tract. Therefore, investigation into the spread of follicular lymphomas in the small bowel is important in order to determine the most appropriate treatment strategy. The performance of double-balloon endoscopy (DBE) in the diagnosis of jejunoileal follicular lymphoma lesions has not been fully evaluated. We aimed to investigate the value of DBE in addition to computed tomography (CT) and 18F-fluorodeoxyglucose positron emission tomography (18F-FDG-PET) in the diagnosis of jejunoileal follicular lymphoma. DBE with biopsy was performed in seven patients with primary duodenal follicular lymphoma diagnosed by EGD, in order to investigate jejunoileal involvement. Jejunoileal follicular lymphoma lesions were detected by DBE in six out of the seven patients (three in the jejunum and three in the jejunum and ileum), whereas CT and 18F-FDG-PET failed to detect the existence of these lesions. Endoscopic findings of the jejunoileal lesions revealed multiple white nodules and white villi, which were similar to those of duodenal lesions. DBE was more useful for the diagnosis of jejunoileal involvement in primary intestinal follicular lymphoma than CT and 18F-FDG-PET. The use of DBE will become important for determining the most appropriate treatment for gastrointestinal follicular lymphoma.

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K. NakamuraMD, PhD 

Department of Medicine and Bioregulatory Science
Graduate School of Medical Sciences
Kyushu University

3-1-1, Maidashi
Higashi-ku
Fukuoka 812-8582
Japan

Fax: +81-92-6425287

eMail: knakamur@intmed3.med.kyushu-u.ac.jp