Klin Monbl Augenheilkd 2009; 226(11): 914-920
DOI: 10.1055/s-0028-1109650
Übersicht

© Georg Thieme Verlag KG Stuttgart · New York

Neue therapeutische Ansätze in der Behandlung der Frühgeborenenretinopathie

New Therapeutic Approaches in the Treatment of Retinopathy of PrematurityC. Jandeck1
  • 1Augenheilkunde, Artemis Zentren Frankfurt
Weitere Informationen

Publikationsverlauf

Eingegangen: 20.4.2009

Angenommen: 22.6.2009

Publikationsdatum:
01. Oktober 2009 (online)

Zusammenfassung

Dieser Übersichtsartikel beschreibt die neuesten Entwicklungen im Bereich der Therapie der Frühgeborenenretinopathie (RPM). Kenntnisse über dieses meist bei extrem unreifen Säuglingen auftretende Krankheitsbild sind weiterhin wichtig, da trotz verbesserter neonatologischer Intensivmedizin die RPM weiterhin auftritt und durch eine Therapie zum optimalen Zeitpunkt das Erblindungsrisiko deutlich reduziert werden kann. Die aktuelle deutsche Richtlinie zur Screening-Untersuchung und Therapie wird beschrieben. Die verschiedenen aktuellen Therapiemöglichkeiten und Behandlungsergebnisse werden diskutiert. Es erfolgt eine Übersicht über die derzeitigen Studien und Fallberichte der zukünftigen möglichen, vielversprechenden Behandlungsmethode mit dem Anti-VEGF-Medikament Bevacizumab.

Abstract

This review highlights recent advances in clinical research on the therapy for retinopathy of prematurity (ROP). This disease is still important, because improvements in neonatal intensive care during the last years have increased the survival of the most immature newborns, but have not diminished the ROP frequency. Laser treatment at the optimal time for advanced ROP mostly prevents blindness. This paper describes the classification, current German screening criteria and the modern concept of ROP pathophysiology. The therapeutic treatment strategies and the treatment results, as well the possible promising future therapy with anti-VEGF (bevacizumab) is discussed.

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Dr. Claudia Jandeck

Augenheilkunde, Artemis Zentren Frankfurt

Kennedyallee 55

60596 Frankfurt

Telefon: ++ 49/69/69 76 97 69

Fax: ++ 49/69/69 76 97 66

eMail: c.jandeck@artemiskliniken.de