Intramural Stomach Injection under Direct Gastrofiberscope Observation

Summary

For the physiological and pathophysiological study of the stomach, and for application to diagnosis or treatment of gastric cancer, intramural injection of various agents or dyes into the stomach wall under direct vision by a gastrofiberscope was tried and found successful. State of gastric mucosa at the time of injection and movement of the dye after injection were examined by endoscopy or in the resected stomach specimen, and patho-histological examination was made on tissue reaction. Indian ink was found to be a suitable marker for long-term observation of the stomach wall while Evans Blue and Bleu Patenté were suitable for a short period of observation. Injection of Indian ink on the mucosal fold and long-term observation by endoscopy indicated the constancy of folds in the anterior wall of the corpus. Local treatment of gastric cancer by intramural injection was attempted, and the possibility of local treatment of early gastric cancer was suggested.

Key-Words

Intramural stomach injection - gastrofiberscope - constancy of gastric mucosal folds - early gastric cancer - gastric ulcer