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Planta Med 1978; 33(4): 393-395
DOI: 10.1055/s-0028-1097399
Research Articles

© Georg Thieme Verlag Stuttgart · New York

Spectrofluorometric Determination of Sennosides in Tablets

A. M. Wahbi1 , B. Unterhalt2
  • 1Faculty of Pharmacy, University of Alexandria, Egypt.
  • 2Fachbereich Pharmazie und Lebensmittelchemie, Universität Marburg, Bundesrepublik Deutschland.
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Publication History

Publication Date:
13 January 2009 (online)

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Abstract

A rapid fluorometric method for the determination of sennosides (A and B) in tablets is described. The method is based on the reduction of sennosides by sodium dithionite in 0.05M borax to give 1,8 dihydroxy–3–carboxylic acid anthranol. The latter possesses activation and emission wavelengths at 388 and 496 nm, respectively. The mean percentage recovery of 27 tablets was found to be 100.3 + 2.30.

Key Word Index

Sennosides - Fluorometric Determination