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Planta Med 1979; 35(2): 162-166
DOI: 10.1055/s-0028-1097198
Research Articles

© Georg Thieme Verlag Stuttgart · New York

Metabolism of Digitoxin in Individual Plants of Digitalis lanata

Elmar W. Weiler
  • Lehrstuhl für Pflanzenphysiologie, Ruhr–Universität Bochum, Federal Republic of Germany.
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Publication Date:
13 January 2009 (online)

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Abstract

Leaf discs of one and two year old plants of Digitalis lanata Ehrh. metabolize 3H–digitoxin to desacetyl lanatoside A, lanatoside A, and the corresponding C–12 hydroxylated compounds, desacetyl lanatoside C and lanatoside C.

Individual plants from different sources show wide variations in their metabolic profile. A simple test for the screening of plant individuals for high C–12 hydroxylation ability is described.

Key Word Index

Digitalis lanata - Cardenolides - Digitoxin Metabolism - 12–Hydroxylation - Screening Techniques