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Horm Metab Res 1973; 5(4): 279-282
DOI: 10.1055/s-0028-1093947
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© Georg Thieme Verlag KG Stuttgart · New York

The Role of Transcortin in the Distribution of Corticosterone in the Rat

Zsuzsanna  Ács , E.  Stark
  • Institute of Experimental Medicine, Hungarian Academy of Sciences, Budapest, Hungary
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Publication History

Publication Date:
07 January 2009 (online)

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Abstract

In rats treated with ACTH for 14 days, 24 hours after the last injection the plasma transcortin level is low. The biological half-life of corticosterone is of the same duration as in the controls; transcortin leaves it unaffected. The distribution volume of corticosterone is significantly higher in the treated than in the control animals and transcortin decreases it in both groups.

Key words

Plasma Transcortin - Corticosterone Biological Half-Life and Distribution Volume - ACTH Treatment