Dehydroepiandrosterone Concentration in Adipose Tissue of Normal and Overweight Subjects

T. Fehér; L. Halmy; L. Bodrogi; M. H. Kazik

doi:10.1055/s-0028-1093616

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Horm Metab Res 1976; 8(5): 372-374
DOI: 10.1055/s-0028-1093616

Originals

Dehydroepiandrosterone Concentration in Adipose Tissue of Normal and Overweight Subjects

T. Fehér¹ , L. Halmy² , L. Bodrogi¹ , M. H. Kazik¹

¹First Department of Medicine, Semmelweis University Medical School, 1083 Budapest, Hungary
²First Department of Medicine, Otto Korvin Hospital, 1071 Budapest, Hungary

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Publication History

Publication Date:
23 December 2008 (online)

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Abstract

Unconjugated dehydroepiandrosterone has been isolated from human abdominal adipose tissue and identified by double isotope derivatization and recrystallization to constant isotope ratio. Gas chromatography with electron capture detection revealed an actual dehydroepiandrosterone concentration between 0.32 to 2.82 µg/g in adipose tissue of normal and overweight subjects. The approximate dehydroepiandrosterone content of the total adipose tissue mass varied between 30 and 173 mg in subjects with severe obesity.

Key words

Dehydroepiandrosterone - Obesity - Adipose Tissue - Gas Chromatography