Synfacts 2009(3): 0347-0347  
DOI: 10.1055/s-0028-1087738
Polymer-Supported Synthesis
© Georg Thieme Verlag Stuttgart ˙ New York

Silica Nanoparticles Catalyzed Addition of Thiols to Alkenes and Alkynes

Contributor(s): Yasuhiro Uozumi, Yoshinori Hirai
S. Banerjee, J. Das, S. Santra*
University of Central Florida, Orlando, USA
Further Information

Publication History

Publication Date:
19 February 2009 (online)

Significance

Silica nanoparticles (silica NPs) catalyzed the anti-Markovnikov addition of thiols to various terminal alkenes and alkynes under solvent-free conditions to give the corresponding thioethers in 85-98% yield (13 examples).