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Synfacts 2009(3): 0310-0310  
DOI: 10.1055/s-0028-1087707
Metal-Mediated Synthesis
© Georg Thieme Verlag Stuttgart ˙ New York

4-MeOC6H4N2 +BF4 -/TiCl3 as an Efficient Mediator for Radical Additions

Contributor(s): Paul Knochel, Tobias Thaler
L. Cao, C. Li*
Shanghai Institute of Organic Chemistry, P. R. of China
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Publication History

Publication Date:
19 February 2009 (online)

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Significance

4-MeOC6H4N2 +BF4 -/TiCl3 is reported as an efficient initiator for ATRA and ATRC reactions under mild conditions in aqueous media. This method can be applied to various alkyl iodides (primary and secondary) and activated alkyl bromides.