Synfacts 2009(3): 0312-0312  
DOI: 10.1055/s-0028-1087706
Metal-Mediated Synthesis
© Georg Thieme Verlag Stuttgart ˙ New York

Stereodefined Cross-Coupling between Allylic Alcohols and Vinyl Silanes

Contributor(s): Paul Knochel, Tobias Thaler
J. K. Belardi, G. C. Micalizio*
Yale University, New Haven, USA
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Publikationsverlauf

Publikationsdatum:
19. Februar 2009 (online)

Significance

A novel olefin functionalization ­reaction via a titanium-mediated reductive cross-coupling between allylic alcohols and vinyl silanes is reported. The reaction proceeds with high dia­stereoselectivity.