Synlett 2008(19): 3046-3052  
DOI: 10.1055/s-0028-1087344
LETTER
© Georg Thieme Verlag Stuttgart ˙ New York

FeCl3-Catalyzed Propargylation-Cycloisomerization Tandem Reaction: A Facile One-Pot Synthesis of Substituted Furans

Wen-hua Ji, Ying-ming Pan, Su-yan Zhao, Zhuang-ping Zhan*
Department of Chemistry, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen 361005, Fujian, P. R. of China
Fax: +86(592)2180318; e-Mail: zpzhan@xmu.edu.cn;
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Publikationsverlauf

Received 1 July 2008
Publikationsdatum:
12. November 2008 (online)

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Abstract

An efficient FeCl3-catalyzed tandem propargylation-­cycloisomerization reaction of propargylic alcohols or acetates with 1,3-dicarbonyl compounds, leading to the synthesis of substituted furans, has been developed.