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DOI: 10.1055/s-0028-1084472
New phenylethanoid glycosides from Jacaranda caucana (Bignoniaceae)
As a part of our ongoing investigations on Bignoniaceae from Panama [1], several species were submitted to a rapid DPPH TLC test for radical scavenging activity. Jacaranda caucana Pittier, a tree which grows from Costa Rica to Colombia, was selected due to its interesting activity, and the lack of phytochemical studies on the polar extract. Nevertheless, several quinones and triterpenes have been already isolated and characterised from the chloroform-soluble fraction of a total methanol extract [2].
The methanol extract has been partitioned between ethyl acetate, butanol and water. The EtOAc fraction was chromatographed on a reverse-phase MPLC column. This separation afforded directly two new phenylethanoid glycosides (1 and 2), along with salicylic acid, acteoside, and jionoside D. Further purifications by semi-preparative HPLC allowed the isolation of isoacteoside and martynoside. The structures were determined by means of spectrometric methods, including 1D and 2D NMR experiments and MS analysis.
![](https://www.thieme-connect.de/media/plantamedica/200809/pb127_1.jpg)
![](https://www.thieme-connect.de/media/plantamedica/200809/pb127_2.jpg)
![](https://www.thieme-connect.de/media/plantamedica/200809/pb127_3.jpg)
Acknowledgements: The authors would like to thank the Swiss National Science Foundation for financial support of this work (grant no. 200020–107775/1 to Prof. K. Hostettmann)
References: 1. Martin, F. et al. (2007) Phytochemistry 68:1307–1311. 2. Ogura, G. et al. (1977) Lloydia 40:157–168.