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Synthesis 2009(5): 775-778
DOI: 10.1055/s-0028-1083347
DOI: 10.1055/s-0028-1083347
PAPER
© Georg Thieme Verlag
Stuttgart ˙ New York
Microwave-Assisted One-Pot Synthesis of (Aminoalkyl)naphthols and (Aminoalkyl)quinolinols by Using Ammonium Carbamate or Ammonium Hydrogen Carbonate as Solid Ammonia Source
Weitere Informationen
Received
3 September 2008
Publikationsdatum:
02. Februar 2009 (online)
Publikationsverlauf
Publikationsdatum:
02. Februar 2009 (online)
![](https://www.thieme-connect.de/media/synthesis/200905/lookinside/thumbnails/10.1055-s-0028-1083347-1.jpg)
Abstract
Ammonium carbamate and ammonium hydrogen carbonate were used as very effective solid ammonia sources to prepare different (aminoalkyl)naphthols and (aminoalkyl)quinolinols in ethanol and water as solvents under microwave conditions in modified three-component Mannich reactions. The products were obtained in excellent yields in one-pot reactions.
Key words
amino alcohols - green chemistry - heterocycles - Mannich bases - multicomponent reactions
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