Synthesis 2009(3): 512-512  
DOI: 10.1055/s-0028-1083326
ADDENDA
© Georg Thieme Verlag Stuttgart ˙ New York

Synthesis and Olfactory Evaluation of (4aR*,8aR*)-1,1,8a-Trimethyl­-decahydronaphthalen-4a-ol: A cis-Decalol Intersection Structure of (-)-Patchoulol and (5R*,6S*)-1,1,6-Trimethylspiro[4.5]decan-6-ol


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Publikationsdatum:
26. Januar 2009 (online)

Inadvertently, instead of (-)-patchoulol, the (+)-enantio­mer was drawn in Figures  [¹] and [²] . As the target compound and all intermediates are racemates, this has no influence on the results, still Figures  [¹] and [²] should be replaced by the correct representations below. For the sake of better correlation, the opposite enantiomer has also been delineated for racemic compounds. The authors apologize for this mistake.

Figure 1 Patchouli odorants, decalin odorants, and the derivation of the cis-decalol intersection target structure 4

Figure 2 Biflexible superposition analysis of (-)-patchoulol (1, depicted­ in silver) on the patchouli-smelling (5R*,6S*)-1,1,6-trimethylspiro[4.5]decan-6-ol (3, displayed in gold) with the MOE 2007.09 software package