Synthesis 2008(22): 3537-3562  
DOI: 10.1055/s-0028-1083210
REVIEW
© Georg Thieme Verlag Stuttgart ˙ New York

Cobalt-Catalysed Carbon-Carbon Bond-Formation Reactions

Wilfried Hess, Jonas Treutwein, Gerhard Hilt*
Fachbereich Chemie, Philipps-Universität Marburg, Hans-Meerwein-Straße, 35043 Marburg, Germany
Fax: +49(6421)2825677; e-Mail: Hilt@chemie.uni-marburg.de;
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Publikationsverlauf

Received 14 May 2008
Publikationsdatum:
27. Oktober 2008 (online)

Abstract

The recent developments in cobalt catalysis are compiled in this review covering the years 2000 through 2007. Special focus is directed towards cobalt-catalysed ring-formation reactions as well as towards cobalt-catalysed (cross-) coupling reactions and synthetically useful applications thereof in the synthesis of acyclic compounds.

1 Introduction

2 Cobalt-Catalysed Cycloaddition Reactions

2.1 Cyclopropanation

2.2 Four-Membered-Ring Formation

2.3 Five-Membered-Ring Formation

2.4 Six-Membered-Ring Formation

2.5 Seven-Membered-Ring Formation

2.6 Eight-Membered-Ring Formation

2.7 Ten-Membered-Ring Formation

3 Cobalt-Catalysed Synthesis of Acyclic Compounds

3.1 Coupling Reactions between Alkenes and Alkynes

3.2 Cross-Coupling Reactions

3.3 Cobalt-Catalysed Coupling Reactions Using Grignard Reagents

3.4 Hydrocyanation, Hydrophosphination, Hydrosilylation and Hydrovinylation Reactions

3.5 Nucleophilic Substitution with Organocobalt Reagents

3.6 Cobalt-Catalysed Carbonylative Ring-Expansion and Ring-Opening Reactions

4 Miscellaneous

5 Conclusions and Outlook