Hepatitis-B-Viruslast als Risikofaktor für eine Leberzirrhose

Schlüsselwörter

Hepatitis B - Viruslast - Leberzirrhose

Key words

hepatitis B - viral load - liver cirrhosis

Literatur

• 1 Chen C J, Yang H I, Su J, Jen C L, You S L, Lu S N, Huang G T, Iloeje U H. Risk of hepatocellular carcinoma across a biological gradient of serum hepatitis B virus DNA level.  JAMA. 2006;  295 65-73
• 2 Chen G, Lin W, Shen F, Iloeje U H, London W T, Evans A A. Past HBV viral load as predictor of mortality and morbidity from HCC and chronic liver disease in a prospective study.  Am J Gastroenterol. 2006;  101 1797-803
• 3 Fattovich G, Olivari N, Pasino M, D’Onofrio M, Martone E, Donato F. Long-term outcome of chronic hepatitis B in Caucasian patients: mortality after 25 years.  Gut. 2008;  57 84-90
• 4 Giovanna F, Bortolotti F, Francesco D. Natural history of chronic hepatitis B: special emphasis on disease progression and prognostic factors.  J Hepatol. 2008;  48 335-52
• 5 Iloeje U H, Yang H I, Su J, Jen C L, You S L, Chen C J. Predicting cirrhosis risk based on the level of circulating hepatitis B viral load.  Gastroenterology. 2006;  130 678-86
• 6 Lai M, Hyatt B J, Nasser I, Curry M, Afdhal N H. The clinical significance of persistently normal ALT in chronic hepatitis B infection.  J Hepatol. 2007;  47 760-7
• 7 Lin C L, Liao L Y, Liu C J, Yu M W, Chen P J, Lai M Y, Chen D S, Kao J H. Hepatitis B viral factors in HBeAg-negative carriers with persistently normal serum alanine aminotransferase levels.  Hepatology. 2007;  45 1193-8
• 8 Lok A S, McMahon B J. Chronic hepatitis B.  Hepatology. 2007;  45 507-39
• 9 Manno M, Camma C, Schepis F, Bassi F, Gelmini R, Giannini F, Piselli F, Grottola A, Ferretti I, Vecchi C, De Palma M, Villa E. Natural history of chronic HBV carriers in northern Italy: morbidity and mortality after 30 years.  Gastroenterology. 2004;  127 756-63
• 10 Thimme R, Spangenberg H C, Blum H E. Chronische Hepatitis B.  Dtsch Med Wochenschr. 2008;  133 135-8
• 11 Wedemeyer H, Cornberg M, Protzer U, Berg T, Dollinger M M. German guidelines on diagnosis and therapy of hepatitis B.  Dtsch Med Wochenschr. 2007;  132 1775-82
• 12 Yang H I, Lu S N, Liaw Y F, You S L, Sun C A, Wang L Y, Hsiao C K, Chen P J, Chen D S, Chen C J. Hepatitis B e antigen and the risk of hepatocellular carcinoma.  N Engl J Med. 2002;  347 168-74