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DOI: 10.1055/a-2650-6278
Tailored-Designed Ligands for Enantioselective Gold(I)-Catalyzed Activation of Alkynes
Autor*innen
Gefördert durch: AGAUR 2021 SGR 01256
Gefördert durch: CERCA Program/Generalitat de Catalunya
Gefördert durch: MICIU 501100011033/FEDER,CEX2019-000925-S/MICIU/AEI/10.13,PID2022-136623NB-I00/MICIU/AEI/10.13039
Gefördert durch: European Research Council 835080
Funding Information We thank the MICIU (PID2022-136623NB-I00/MICIU/AEI/10.13039 /501100011033/FEDER), UE and Severo Ochoa Excellence Accreditation CEX2024-001469-S funded by MCIU/AEI/10.13039/501100011033, the European Research Council (Advanced Grant 835080), the AGAUR (2021 SGR 01256), and the CERCA Program/Generalitat de Catalunya for financial support.
Abstract
In this article, we describe the work performed at our laboratories over the years on the design and applications of novel chiral ligands for the enantioselective gold(I)-catalyzed activation of alkynes, with a focus on the cycloisomerization and cycloaddition reactions of 1,6-enynes. The rationale behind the development of each ligand and the mode of enantioinduction are discussed.
Publikationsverlauf
Eingereicht: 11. Mai 2025
Angenommen nach Revision: 03. Juli 2025
Accepted Manuscript online:
07. Juli 2025
Artikel online veröffentlicht:
20. August 2025
© 2025. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/).
Georg Thieme Verlag KG
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