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CC BY 4.0 · Endosc Int Open 2025; 13: a25399167
DOI: 10.1055/a-2539-9167
Innovation forum

Novel endoscopic gastric purse-string suture device for weight management in a porcine model (with video)

Yiyu Qiao‡
1   Department of Gastroenterology, the 5th Medical Center of PLA General Hospital, Beijing, China (Ringgold ID: RIN26460)
,
Shuqian Hu‡
1   Department of Gastroenterology, the 5th Medical Center of PLA General Hospital, Beijing, China (Ringgold ID: RIN26460)
2   The School of Medicine, Nankai University, Nankai District, Tianjin, China (Ringgold ID: RIN12538)
,
Wei Shen
3   Department of Gastroenterology, Senior Department of Gastroenterology, the 1st Medical Center of PLA General Hospital, Beijing, China (Ringgold ID: RIN678390)
,
Airong Tang
1   Department of Gastroenterology, the 5th Medical Center of PLA General Hospital, Beijing, China (Ringgold ID: RIN26460)
,
Xueting Zhang
1   Department of Gastroenterology, the 5th Medical Center of PLA General Hospital, Beijing, China (Ringgold ID: RIN26460)
,
Hanqing Zhang
1   Department of Gastroenterology, the 5th Medical Center of PLA General Hospital, Beijing, China (Ringgold ID: RIN26460)
,
Min Min
3   Department of Gastroenterology, Senior Department of Gastroenterology, the 1st Medical Center of PLA General Hospital, Beijing, China (Ringgold ID: RIN678390)
,
Yan Liu
3   Department of Gastroenterology, Senior Department of Gastroenterology, the 1st Medical Center of PLA General Hospital, Beijing, China (Ringgold ID: RIN678390)
› InstitutsangabenGefördert durch: National Natural Science Foundation of China 8217032560
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Abstract

Obesity is a global health issue. Traditional treatment modalities such as lifestyle modifications, pharmacological interventions, and bariatric surgery often present various limitations. Recently, endoscopic bariatric and metabolic therapies (EBMTs) have emerged as promising minimally invasive approaches for weight management. These therapies reduce gastric volume and energy intake, prolong gastric emptying, and regulate hormones associated with satiety. This study evaluated endoscopic gastric purse-string suturing (EGPSS), a novel endoscopic procedure designed to reduce gastric fundus volume while minimizing associated risks. We assessed its feasibility and efficacy in a porcine model in terms of histological, physiological, and metabolic outcomes. The results suggest that EGPSS offers a viable option for metabolic control.

Keywords

Quality and logistical aspects - Performance and complications - Training - GI surgery

Supplementary Material



Publikationsverlauf

Eingereicht: 13. September 2024

Angenommen nach Revision: 07. Februar 2025

Accepted Manuscript online:
14. Februar 2025

Artikel online veröffentlicht:
15. April 2025

© 2025. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. (https://creativecommons.org/licenses/by/4.0/).

Georg Thieme Verlag KG
Oswald-Hesse-Straße 50, 70469 Stuttgart, Germany

Bibliographical Record
Yiyu Qiao, Shuqian Hu, Wei Shen, Airong Tang, Xueting Zhang, Hanqing Zhang, Min Min, Yan Liu. Novel endoscopic gastric purse-string suture device for weight management in a porcine model (with video). Endosc Int Open 2025; 13: a25399167.
DOI: 10.1055/a-2539-9167
 

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